We are pleased to report the award of funding from the National Institute of Environmental Health Sciences for a two year study in which we will carry out intensive molecular genetic and biochemical/toxicological studies in people and animal models.
We are grateful in reporting the 31st year of continuous funding from the Les Turner ALS Foundation for infrastructure support. This crucial funding supports salaries of research personnel and buy and service equipment used to maintain our cell and tissue banks and genotyping capabilities. And, for the 22nd year, the Foundation is providing support to the Lois Insolia Read more about The Les Turner ALS Foundation continues to support research in ALS[…]
H-X Deng, MD, PhD is the lead author of a publication in online Annals of Neurology that reports the presence of FUS immunoreactive inclusions in postmortem spinal cord tissue from patients with both sporadic and familial ALS (FALS). These findings provide a new basis for investigation of a rational therapy that may be effective for SALS and FALS. Read more about We identify FUS immunoreactive inclusions in both sporadic ALS and familial ALS[…]
Our team has identified mutations in the TRPV4 gene as causative in two related degenerative motor nerve disorders, scapuloperoneal spinal muscular atrophy (SPSMA) and hereditary motor and sensory neuropathy type IIC (CMT2C).